Bioinformatics Developer

 
  • EMBL
  • United Kingdom
  • Sep 29, 2021
Science Full Time - Fixed Term

Job Description:

As a Bioinformatics Developer in our PDCM Team, you will have an exciting opportunity to design and develop new interfaces to explore one of the fundamental problems of biology - how do our genes contribute to cancer?

The PDCM Finder team is looking for an energetic Bioinformatics Developer to help extend an existing cancer model platform (www.pdxfinder.org). Our team harmonises, analyses and disseminates rich omic and phenotypic data from Patient Derived Xenograft (PDX), organoid, and cancer cell line models to produce a unified catalog of cancer research materials and data. These resources advance cancer research by enabling researchers to find and obtain relevant data and models. We adhere to the Findable, Accessible, Interoperable, Reusable (FAIR) data principles in order to maximize the availability and reach of cancer research models to the wider scientific community. 

PDX, organoids and cell line models are used to investigate human cancers and are increasingly being used in clinical research to test new chemotherapeutic regimes and study drug resistance mechanisms. The PDCM Finder integrates cancer model data from multiple international sources and leverages EMBL-EBI’s resources that store genomic and transcriptomic data.



You’ll be part of the Samples, Phenotypes and Ontologies Team (SPOT) at EMBL-EBI alongside developers, bioinformaticians and ontologists. This project presents an interesting opportunity for the presentation of complex biological data to users in intuitive, visually appealing ways. You will be helping to extend the metadata of PDCM Finder to cell lines and organoids models and managing the data for the world’s largest open PDX model catalog. 

You’ll be involved in soliciting user feedback and will need to be responsive to evolving requirements. As part of your day to day job, you’ll be working in an agile team  with expertise in software design and engineering, semantics, data science, image analysis and 3D image display.

You’ll also interact with other groups at EMBL-EBI and external collaborators, both within the UK and internationally, to improve our websites.





Do something meaningful
At EMBL-EBI you can apply your talent and passion to accelerate science and tackle some of humankind's greatest challenges. EMBL-EBI, part of the European Molecular Biology Laboratory, is a worldwide leader in the storage, analysis and dissemination of large biological datasets. We provide the global research community with access to publicly available databases and tools which are crucial for the advancement of healthcare, food security, and biodiversity. Join a culture of innovation
We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential.  Enjoy lots of benefits: For more details please see our employee benefits page.