Scientific Officer - Protein Expression and Purification Core Facility

  • EMBL
  • Germany
  • Dec 23, 2021
Science Full Time - Fixed Term

Job Description:

The EMBL Protein Expression and Purification Core Facility provides support regarding all types of experiments related to advanced protein expression, purification and biophysical characterization. The facility offers a service for high-quality protein production in E. coli, insect and mammalian cells, whilst also maintaining a state-of-the-art biophysics platform for protein characterization and interaction studies.

In this role, your main responsibility will be to perform recombinant protein expression and purification experiments in insect and mammalian cells. You will be expected to discuss the project needs with individual users and then develop a suitable strategy for the construct design, expression and purification of the requested recombinant proteins. Quality control of the purified proteins will be done in close collaboration with the facility's biophysics platform. Furthermore, the new scientific officer will also take part in the development and optimization of novel methods and protocols with the aim of developing robust and efficient pipelines adapted to the requirements of our users.  

The minimum requirement for this position is a degree in biochemistry, molecular biology or in a closely related scientific area. Expertise in the field of protein expression in eukaryotic cells on the milligram scale and a broad experience with protein purification using a combination of chromatographic techniques on automated chromatography workstations is absolutely essential. Teamwork, flexibility, strong organizational skills and the ability to interact with a varied multicultural user community are expected. Fluency in English is required.

A good working knowledge of various cloning methods would be considered an advantage for this position.

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises from a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including your family and the availability of an excellent child care facility on campus.

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1600 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research.

Please note that appointments on fixed term contracts can be renewed for up to 9 years in total, depending on circumstances at the time of the review.